SCHEMBL29925017

SCHEMBL29925017

N=C(N)NCCC[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(c2ccccc2)c2ccccc2)NC(=O)[C@H](C(c2ccccc2)c2ccccc2)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SSTR2 P30874 5/20 0.51
SSTR5 P35346 5/20 0.51
SSTR3 P32745 4/20 0.51
SSTR1 P30872 3/20 0.51
SSTR4 P31391 3/20 0.51
KDM4A O75164 1/20 0.49
HDAC8 Q9BY41 2/20 0.46
MC4R P32245 9/20 0.45
MC5R P33032 9/20 0.45
MC3R P41968 9/20 0.45
MC1R Q01726 9/20 0.45
HDAC3 O15379 2/20 0.44
HDAC1 Q13547 2/20 0.44
NCOR2 Q9Y618 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29925316 1.00 SSTR2 (0.51) SSTR2SSTR5SSTR3SSTR1SSTR4
SCHEMBL29925290 1.00 SSTR2 (0.51) SSTR2SSTR5SSTR3SSTR1SSTR4
SCHEMBL29925429 1.00 SSTR2 (0.51) SSTR2SSTR5SSTR3SSTR1SSTR4
SCHEMBL29924816 1.00 SSTR2 (0.51) SSTR2SSTR5SSTR3SSTR1SSTR4
SCHEMBL29925303 1.00 SSTR2 (0.51) SSTR2SSTR5SSTR3SSTR1SSTR4
SCHEMBL29925512 0.87 TPSAB1 (0.40) KDM4A
SCHEMBL29925126 0.87 TPSAB1 (0.40) KDM4A
SCHEMBL29925086 0.87 TPSAB1 (0.40) KDM4A
SCHEMBL29925039 0.87 TPSAB1 (0.40) KDM4A
SCHEMBL29925101 0.87 TPSAB1 (0.40) KDM4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES AJK BIOPHARMACEUTICAL LLC (US) 2022-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220289794-A1 SYNTHETIC ANTIMICROBIAL PEPTIDES VIP, HM13, NGLY1 SSTR2 2093/4885SSTR5 1501/4885SSTR3 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.