Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30085747 | 0.91 | POLB (0.34) | SIGMAR1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL29925418 | 0.89 | POLB (0.35) | CHRM2CHRM4HTR1ACHRM5CHRM1 | |
| SCHEMBL29924890 | 0.87 | BCHE (0.32) | CHRM2CHRM4HTR1ACHRM5CHRM1 | |
| SCHEMBL30085741 | 0.87 | CACNA1C (0.41) | SIGMAR1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL29924955 | 0.86 | MEN1 (0.37) | CHRM2CHRM4HTR1ACHRM5CHRM1 | |
| SCHEMBL30085704 | 0.85 | SMPD1 (0.37) | CHRM2CHRM4HTR1ACHRM5CHRM1 | |
| SCHEMBL30085762 | 0.85 | BCHE (0.33) | SIGMAR1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL29924716 | 0.85 | HRH3 (0.42) | CHRM1HTR2ACYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL30085736 | 0.85 | MAPK13 (0.36) | SIGMAR1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL30085743 | 0.84 | KDM4E (0.37) | CHRM2CHRM4HTR1ACHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |