Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30085747 | 0.88 | POLB (0.34) | HRH3CHRM1HTR2ACYP2D6CYP2C19 | |
| SCHEMBL29925418 | 0.86 | POLB (0.35) | HRH3CHRM1HTR2ACYP2D6CYP2C19 | |
| SCHEMBL30085741 | 0.86 | CACNA1C (0.41) | HRH3CHRM1HTR2ACYP2D6CYP2C19 | |
| SCHEMBL29925189 | 0.85 | SIGMAR1 (0.34) | HRH3CHRM1HTR2ACYP2D6CYP2C19 | |
| SCHEMBL29924890 | 0.84 | BCHE (0.32) | HRH3CHRM1HTR2AKDM4EALDH1A1 | |
| SCHEMBL29924955 | 0.83 | MEN1 (0.37) | HRH3CHRM1HTR2AMEN1ALDH1A1 | |
| SCHEMBL30085762 | 0.82 | BCHE (0.33) | HRH3CHRM1HTR2ACYP2D6CYP2C19 | |
| SCHEMBL30085704 | 0.82 | SMPD1 (0.37) | HRH3CHRM1HTR2AMCHR1KDM4E | |
| SCHEMBL30085734 | 0.82 | KDM4E (0.38) | HRH3CHRM1HTR2AKDM4EMEN1 | |
| SCHEMBL30085736 | 0.82 | MAPK13 (0.36) | HRH3CHRM1HTR2ACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |