Formic Acid

Formic Acid

SCHEMBL29925333

CCc1nccn1CCNC(=O)c1ccc2c(c1)sc1nc(-c3ccc(C(=O)NC)cc3)cn12.CCc1nccn1CCNC(=O)c1ccc2c(c1)sc1nc(-c3ccc(C(=O)NC)cc3)cn12.O=CO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.58
▸ TP53 P04637 2/20 0.54
▸ MAPT P10636 7/20 0.53
▸ THRB P10828 3/20 0.53
▸ POLB P06746 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ RXFP1 Q9HBX9 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24619767 0.97 LMNA (0.62) LMNATP53MAPTTHRBPOLB
Formic Acid SCHEMBL29925647 0.83 LMNA (0.64) LMNATP53MAPTTHRBPOLB
Formic Acid SCHEMBL29925480 0.81 MAPT (0.58) LMNATP53MAPTTHRBPOLB
SCHEMBL24741269 0.80 LMNA (0.68) LMNATP53MAPTTHRBPOLB
SCHEMBL24741290 0.79 LMNA (0.67) LMNATP53MAPTTHRBPOLB
Formic Acid SCHEMBL29925406 0.79 LMNA (0.55) LMNATP53MAPTTHRBPOLB
SCHEMBL24619803 0.79 LMNA (0.68) LMNATP53MAPTTHRBPOLB
SCHEMBL24619719 0.79 LMNA (0.68) LMNATP53MAPTTHRBRXFP1
SCHEMBL24619396 0.79 TP53 (0.73) LMNATP53MAPTTHRBPOLB
Formic Acid SCHEMBL29924881 0.79 LMNA (0.63) LMNATP53MAPTTHRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4274569-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2023-11-15 — — EP disclosed
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-11-24 — — US disclosed
WO-2022150316-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2022-07-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220370431-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 LMNA 1484/4885TP53 96/4885MAPT 3215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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