Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.46 |
| ▸ | CDK4 | P11802 | 4/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | CCND3 | P30281 | 2/20 | 0.40 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.40 |
| ▸ | WEE1 | P30291 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14913056 | 1.00 | BTK (0.46) | BTKCDK4CCNA2CCND1CCNE1 | |
| SCHEMBL14913053 | 1.00 | BTK (0.46) | BTKCDK4CCNA2CCND1CCNE1 | |
| SCHEMBL10256584 | 0.84 | CCND3 (0.48) | CDK4CCNA2CCND1CCNE1CDK2 | |
| SCHEMBL14930391 | 0.83 | CDK4 (0.42) | BTKCDK4CCNA2CCND1CCNE1 | |
| SCHEMBL19947368 | 0.83 | CDK4 (0.42) | BTKCDK4CCNA2CCND1CCNE1 | |
| SCHEMBL31158061 | 0.83 | CDK4 (0.42) | BTKCDK4CCNA2CCND1CCNE1 | |
| Hydrochloric Acid SCHEMBL1393269 | 0.83 | CDK2 (0.47) | CDK4CCNA2CCND1CCNE1CDK2 | |
| SCHEMBL14912860 | 0.81 | BTK (0.51) | BTKCDK4CCNA2CCND1CCNE1 | |
| SCHEMBL14916485 | 0.81 | BTK (0.51) | BTKCDK4CCNA2CCND1CCNE1 | |
| SCHEMBL29741805 | 0.81 | BTK (0.51) | BTKCDK4CCNA2CCND1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270747-A1 | HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS | GENENTECH, INC. (US) | 2024-08-15 | — | — | US | disclosed |
| EP-4050012-A1 | PYRIDONE BORONATES FOR THE PREPARATION OF INHIBITORS OF BTK ACTIVITY | F. Hoffmann-La Roche AG (CH) | 2022-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240270747-A1 | HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS | PDXK, BTK, TYK2 | BTK 2/4885CDK4 170/4885CCNA2 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.