Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 9/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31712846 | 0.79 | LCK (0.40) | LCKEGFRADORA3TSHRMC4R | |
| SCHEMBL29926108 | 0.78 | LCK (0.49) | LCKEGFRLMNAAR | |
| SCHEMBL5173369 | 0.76 | LCK (0.56) | LCKEGFRADORA3TSHRMC4R | |
| SCHEMBL29649950 | 0.74 | EGFR (0.56) | LCKEGFRARPIK3CDPIK3CA | |
| SCHEMBL7145196 | 0.74 | LCK (0.47) | LCKTSHRLMNAARKMT2A | |
| SCHEMBL5676295 | 0.74 | EGFR (0.56) | LCKEGFRARPIK3CDPIK3CA | |
| SCHEMBL27881435 | 0.72 | EGFR (0.54) | LCKEGFRARPIK3CDPIK3CA | |
| SCHEMBL5566411 | 0.71 | LCK (0.41) | LCKEGFRADORA3TSHRMC4R | |
| SCHEMBL20950927 | 0.71 | LCK (0.49) | LCKADORA3TSHRMC4RADRA1A | |
| SCHEMBL6364161 | 0.71 | EGFR (0.57) | EGFRPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315424-A | 2-methyl-aza-quinazolines | 拜耳公司 | 2022-11-08 | — | — | CN | claimed |
| CN-115315424-A | 2-methyl-aza-quinazolines | 拜耳公司 | 2022-11-08 | — | — | CN | disclosed |