Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 11/20 | 0.34 |
| ▸ | AKT1 | P31749 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31712895 | 0.80 | CSNK2A2 (0.43) | CSNK2A2CSNK2BEGFR | |
| SCHEMBL29925974 | 0.79 | LCK (0.45) | LCKADORA3TSHRMC4RADRA1A | |
| SCHEMBL31712862 | 0.78 | KDM4E (0.48) | LCKADORA3TSHRMC4RADRA1A | |
| SCHEMBL16447402 | 0.77 | LCK (0.40) | LCKADORA3TSHRMC4RADRA1A | |
| SCHEMBL29800333 | 0.76 | CSNK2A2 (0.51) | CSNK2A2CSNK2B | |
| SCHEMBL29685908 | 0.73 | CCNA2 (0.38) | LCKSIRT6KMT2A | |
| SCHEMBL31712899 | 0.69 | SIRT6 (0.37) | LCKADORA3TSHRMC4RADRA1A | |
| SCHEMBL29875481 | 0.69 | BTK (0.41) | LCKADORA3TSHRMC4RADRA1A | |
| SCHEMBL6360085 | 0.69 | IP6K1 (0.52) | AKT1 | |
| SCHEMBL31712880 | 0.68 | PARP1 (0.39) | LCKADORA3TSHRMC4RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251624-B1 | TRICYCLIC CARBOXAMIDE DERIVATIVES AS PRMT5 INHIBITORS | AMGEN INC (US) | 2025-10-29 | — | — | EP | claimed |