Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011288 | 1.00 | AHR (0.64) | AHRMAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL5341593 | 0.78 | AHR (1.00) | AHRMAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL8650444 | 0.77 | MAPT (0.44) | AHRMAPTPARP1CYP3A4TSHR | |
| SCHEMBL30983620 | 0.77 | PARP1 (0.65) | MAPTPARP1CYP3A4TSHRPIK3CA | |
| SCHEMBL3073008 | 0.77 | PARP1 (0.65) | MAPTPARP1CYP3A4TSHRPIK3CA | |
| SCHEMBL8030947 | 0.77 | ALDH1A1 (0.55) | AHRMAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL6185787 | 0.76 | MCL1 (0.62) | MAPTNPC1L3MBTL1PARP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9445592 | 0.75 | ALDH1A1 (0.53) | AHRMAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL21646227 | 0.75 | AHR (0.64) | AHRMAPTNPC1MAPK1L3MBTL1 | |
| SCHEMBL5503927 | 0.75 | AHR (0.64) | AHRMAPTNPC1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087658-A | Sulfonamide or sulfenamide compounds having BRD 4-inducing proteolytic activity, and pharmaceutical use thereof | 田边三菱制药株式会社 | 2022-09-20 | — | — | CN | disclosed |