SCHEMBL29926296

SCHEMBL29926296

O=C(NCC1CC1)c1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 3/20 0.59
MLYCD O95822 1/20 0.59
MAPK14 Q16539 4/20 0.56
AR P10275 1/20 0.55
CACNA1H O95180 1/20 0.54
CA2 P00918 1/20 0.54
HDAC4 P56524 2/20 0.54
HDAC3 O15379 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC9 Q9UKV0 1/20 0.54
HDAC5 Q9UQL6 1/20 0.54
KMT2A Q03164 1/20 0.53
NAMPT P43490 1/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4003531 0.95 HDAC6 (0.55) HDAC6MLYCDMAPK14ARCACNA1H
SCHEMBL4518870 0.92 HDAC6 (0.71) HDAC6MLYCDCA2KMT2ANAMPT
SCHEMBL17730110 0.87 ALDH1A1 (0.67) HDAC6MLYCDMAPK14ARHDAC4
SCHEMBL4013476 0.87 NAMPT (0.59) HDAC6MLYCDARHDAC3KMT2A
SCHEMBL17730108 0.87 ALDH1A1 (0.67) HDAC6MLYCDMAPK14ARHDAC4
SCHEMBL6636825 0.86 CACNA1H (0.50) HDAC6MLYCDMAPK14ARCACNA1H
SCHEMBL6638373 0.86 CACNA1H (0.50) HDAC6MLYCDMAPK14ARCACNA1H
SCHEMBL4013615 0.86 ALDH1A1 (0.60) HDAC6MLYCDMAPK14ARCACNA1H
SCHEMBL6636821 0.84 CACNA1H (0.48) HDAC6MLYCDMAPK14ARCACNA1H
SCHEMBL21693645 0.84 AR (0.52) HDAC6MLYCDMAPK14ARCACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115872889-B Method for preparing o-trifluoromethyl aniline compound 沈阳中化农药化工研发有限公司 2024-10-18 CN disclosed
CN-115606595-A Pesticide composition and application thereof 深圳诺普信农化股份有限公司 2023-01-17 CN disclosed
CN-115053910-A Pesticide composition and application thereof 江苏明德立达作物科技有限公司 2022-09-16 CN disclosed
CN-114847296-A Pesticide microcapsule suspension-suspending agent and preparation method and application thereof 江苏明德立达作物科技有限公司 2022-08-05 CN disclosed