Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | F7 | P08709 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | F3 | P13726 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | PPARD | Q03181 | 2/20 | 0.60 |
| ▸ | PPARA | Q07869 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729032 | 1.00 | OXER1 (0.60) | OXER1ALDH1A1F7CYP19A1F3 | |
| SCHEMBL23628381 | 0.95 | ALDH1A1 (0.62) | OXER1ALDH1A1F7CYP19A1F3 | |
| SCHEMBL12512874 | 0.92 | OXER1 (0.58) | OXER1ALDH1A1F7CYP19A1F3 | |
| SCHEMBL12772434 | 0.92 | OXER1 (0.58) | OXER1ALDH1A1F7CYP19A1F3 | |
| SCHEMBL12512880 | 0.92 | OXER1 (0.58) | OXER1ALDH1A1F7CYP19A1F3 | |
| SCHEMBL30468681 | 0.92 | OXER1 (0.58) | OXER1ALDH1A1F7CYP19A1F3 | |
| SCHEMBL1377700 | 0.92 | OXER1 (0.58) | OXER1ALDH1A1F7CYP19A1F3 | |
| SCHEMBL16237682 | 0.92 | OXER1 (0.58) | OXER1ALDH1A1F7CYP19A1F3 | |
| SCHEMBL904542 | 0.91 | OXER1 (0.73) | OXER1ALDH1A1CYP19A1KMT2APPARG | |
| SCHEMBL6051176 | 0.91 | OXER1 (0.73) | OXER1ALDH1A1CYP19A1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479802-B2 | Assays for screening activity of modulators of members of the hydroxy steroid (17-beta) dehydrogenase (HSD17B) family | REGENERON PHARMACEUTICALS, INC. (US) | 2022-10-25 | — | — | US | disclosed |