Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3153788 | 1.00 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1LMNALCK | |
| SCHEMBL30555263 | 0.85 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1LMNALCK | |
| SCHEMBL9901479 | 0.85 | MAPK1 (0.59) | MAPK1KDM4EL3MBTL1LMNALCK | |
| SCHEMBL2304195 | 0.83 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1LCKCA12 | |
| SCHEMBL3451428 | 0.81 | NAMPT (0.46) | KDM4EL3MBTL1LMNACA2P4HTM | |
| SCHEMBL12481577 | 0.81 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1LMNALCK | |
| SCHEMBL19249701 | 0.81 | MAPK1 (0.54) | MAPK1KDM4EL3MBTL1LMNAP4HTM | |
| SCHEMBL3449352 | 0.77 | KMT2A (0.47) | KDM4ELMNALCKCA12CA1 | |
| SCHEMBL28005239 | 0.77 | MAPK1 (0.50) | MAPK1KDM4EL3MBTL1LMNALCK | |
| SCHEMBL118882 | 0.77 | CA1 (0.61) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087658-A | Sulfonamide or sulfenamide compounds having BRD 4-inducing proteolytic activity, and pharmaceutical use thereof | 田边三菱制药株式会社 | 2022-09-20 | — | — | CN | disclosed |