Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.69 |
| ▸ | CNR2 | P34972 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.69 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.69 |
| ▸ | FAAH | O00519 | 1/20 | 0.69 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927093 | 0.95 | CNR1 (0.69) | CNR1CNR2ALDH1A1MEN1BLM | |
| SCHEMBL29726562 | 0.94 | CNR1 (0.78) | CNR1CNR2ALDH1A1MEN1BLM | |
| SCHEMBL29927289 | 0.94 | CNR1 (0.78) | CNR1CNR2ALDH1A1MEN1BLM | |
| SCHEMBL30600367 | 0.94 | CNR1 (0.78) | CNR1CNR2ALDH1A1MEN1BLM | |
| SCHEMBL29926596 | 0.94 | CNR1 (0.78) | CNR1CNR2ALDH1A1MEN1BLM | |
| SCHEMBL4365145 | 0.86 | EPHX2 (0.56) | CNR1CNR2ALDH1A1MEN1BLM | |
| SCHEMBL1888424 | 0.86 | EPHX2 (0.56) | CNR1CNR2ALDH1A1MEN1BLM | |
| SCHEMBL12673270 | 0.85 | SLC6A5 (0.58) | CNR1CNR2ALDH1A1MEN1BLM | |
| SCHEMBL1891652 | 0.85 | EPHX2 (0.62) | CNR1ALDH1A1MEN1BLMKMT2A | |
| SCHEMBL1891580 | 0.85 | EPHX2 (0.59) | CNR1CNR2ALDH1A1MEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479802-B2 | Assays for screening activity of modulators of members of the hydroxy steroid (17-beta) dehydrogenase (HSD17B) family | REGENERON PHARMACEUTICALS, INC. (US) | 2022-10-25 | — | — | US | disclosed |