Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22774258 | 1.00 | CES2 (0.41) | CES2TSHRMAPK1NR2E1GPBAR1 | |
| SCHEMBL20615653 | 0.86 | CES2 (0.54) | CES2NOTUMGAARXRARXRB | |
| SCHEMBL28490298 | 0.84 | CES2 (0.43) | CES2TSHRMAPK1NR2E1GPBAR1 | |
| SCHEMBL23590674 | 0.82 | CES2 (0.42) | CES2TSHRMAPK1NR2E1GPBAR1 | |
| SCHEMBL4974165 | 0.81 | CES2 (0.50) | CES2TSHRMAPK1GPBAR1NOTUM | |
| SCHEMBL22572900 | 0.79 | FURIN (0.46) | TSHRFURINALDH1A1 | |
| SCHEMBL9585561 | 0.79 | FURIN (0.41) | TSHRFURINALDH1A1CYP3A4 | |
| SCHEMBL13954751 | 0.78 | CES2 (0.42) | CES2GPBAR1NOTUMMAPT | |
| SCHEMBL19623264 | 0.78 | CES2 (0.42) | CES2GPBAR1NOTUMRXRARXRB | |
| SCHEMBL1660123 | 0.78 | PTGS1 (0.45) | CES2GPBAR1NOTUMGAAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761383-A | Sulfonamide derivatives and uses thereof | 诺瑟拉有限公司 | 2022-07-15 | — | — | CN | disclosed |