SCHEMBL29927712

SCHEMBL29927712

CC(=O)NCC1CCN(Cc2cc(Oc3cnc(N4CCN(CCCO)CC4)nc3)cc(-c3cc(Cl)cc(Cl)c3)c2)CC1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 19/20 0.66
▸ KCNH2 Q12809 1/20 0.40
▸ CACNA1I Q9P0X4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21550731 1.00 FURIN (0.66) FURINKCNH2CACNA1I
SCHEMBL21551065 0.92 FURIN (0.66) FURINKCNH2CACNA1I
SCHEMBL29928637 0.92 FURIN (0.66) FURINKCNH2CACNA1I
SCHEMBL21551095 0.91 FURIN (0.79) FURIN
SCHEMBL21550523 0.90 FURIN (0.69) FURINKCNH2CACNA1I
SCHEMBL29928060 0.90 FURIN (0.69) FURINKCNH2CACNA1I
SCHEMBL21550751 0.90 FURIN (0.69) FURINKCNH2CACNA1I
SCHEMBL26077404 0.89 FURIN (0.64) FURIN
SCHEMBL26077400 0.89 FURIN (0.63) FURINKCNH2CACNA1I
SCHEMBL21551558 0.89 FURIN (0.65) FURINKCNH2CACNA1I

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4058021-A1 SMALL MOLECULE FURIN INHIBITORS FOR TREATING INFECTIOUS DISEASES BP Asset V, Inc. (US) 2022-09-21 — — EP claimed
US-20230011571-A1 SMALL MOLECULE FURIN INHIBITORS FOR TREATING INFECTIOUS DISEASES BP ASSET V, INC. (US) 2023-01-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230011571-A1 SMALL MOLECULE FURIN INHIBITORS FOR TREATING INFECTIOUS DISEASES FURIN, LGMN, PLAU FURIN 1/4885KCNH2 4115/4885CACNA1I 964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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