Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12375337 | 0.90 | CYP3A4 (0.51) | CYP3A4USP2MAPK1SMN1; SMN2SLC5A1 | |
| SCHEMBL656327 | 0.87 | CYP3A4 (0.58) | CYP3A4USP2MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL30792317 | 0.87 | CYP3A4 (0.58) | CYP3A4USP2MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL10963506 | 0.85 | CYP3A4 (0.65) | CYP3A4USP2MAPK1SMN1; SMN2SLC5A1 | |
| SCHEMBL7893039 | 0.81 | CYP3A4 (0.55) | CYP3A4USP2MAPK1SMN1; SMN2SLC5A1 | |
| SCHEMBL22465738 | 0.80 | ABCG2 (0.59) | CYP3A4USP2MAPK1SLC5A1SLC5A2 | |
| SCHEMBL26481061 | 0.80 | CYP3A4 (0.71) | CYP3A4USP2MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL30350587 | 0.80 | CYP3A4 (0.71) | CYP3A4USP2MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL30792196 | 0.80 | ABCG2 (0.41) | CYP3A4USP2MAPK1SMN1; SMN2SLC5A1 | |
| SCHEMBL1939998 | 0.79 | KDM4E (0.48) | CYP3A4USP2MAPK1SMN1; SMN2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479537-B2 | T-type calcium channel inhibitor | KINKI UNIVERSITY (JP) | 2022-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11479537-B2 | T-type calcium channel inhibitor | CACNA1H, CACNA1I, CACNA1G | CYP3A4 2884/4885USP2 4322/4885MAPK1 1210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.