2-Phenylbenzo[D]Thiazole

2-Phenylbenzo[D]Thiazole

SCHEMBL29928313

[Ir].c1ccc(-c2nc3ccccc3s2)cc1.c1ccc(-c2nc3ccccc3s2)cc1.c1ccc(-c2nc3ccccc3s2)cc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.72
NPC1 O15118 5/20 0.72
KDM4E B2RXH2 5/20 0.72
APP P05067 5/20 0.70
MAPT P10636 4/20 0.70
ALDH1A1 P00352 3/20 0.70
GLA P06280 3/20 0.70
GAA P10253 3/20 0.70
LMNA P02545 2/20 0.70
MMP9 P14780 2/20 0.70
MMP8 P22894 2/20 0.70
SMN1; SMN2 Q16637 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
NFKB1 P19838 2/20 0.64
NFKB2 Q00653 2/20 0.64
RELA Q04206 2/20 0.64
PKM P14618 2/20 0.64
PAX8 Q06710 1/20 0.64
NOD2 Q9HC29 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenylbenzo[D]Thiazole SCHEMBL27607988 1.00 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL2453217 1.00 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL3371957 1.00 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL30988131 0.98 RAB9A (0.75) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL94005 0.98 RAB9A (0.75) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL29986751 0.96 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL27839442 0.96 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
2-Phenylbenzo[D]Thiazole SCHEMBL27949942 0.96 RAB9A (0.72) RAB9ANPC1KDM4EAPPMAPT
SCHEMBL754574 0.94 RAB9A (0.73) RAB9ANPC1KDM4EAPPMAPT
SCHEMBL29474819 0.91 RAB9A (0.81) RAB9ANPC1KDM4EAPPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023058644-A1 COMPOUND, ORGANIC EL ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE 東レ株式会社 2023-04-13 WO disclosed
WO-2022181197-A1 ORGANIC EL ELEMENT MATERIAL, ORGANIC EL ELEMENT, DISPLAY DEVICE, AND ILLUMINATION DEVICE 東レ株式会社 2022-09-01 WO disclosed