Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.54 |
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | TLR4 | O00206 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21657641 | 1.00 | MAOA (0.54) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL13577707 | 0.92 | MAOA (0.53) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL15426822 | 0.90 | MAOA (0.60) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL22181586 | 0.90 | MAOA (0.60) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL5543437 | 0.88 | MAOA (0.66) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL16451156 | 0.86 | TLR4 (0.57) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL5255935 | 0.86 | NPC1 (0.55) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL30461144 | 0.86 | NPC1 (0.55) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL4748638 | 0.86 | NPC1 (0.55) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL30622749 | 0.86 | NPC1 (0.55) | MAOAMAOBNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638477-B | Pyrrolo [2,3-B ] pyridine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-110637022-B | Pyrrolopyrimidine derivatives as inhibitors of influenza virus replication | 共晶制药公司 | 2022-09-16 | — | — | CN | disclosed |