Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 6/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 6/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.46 |
| ▸ | CHRNB3 | Q05901 | 6/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4992964 | 0.72 | AXL (0.76) | AXL | |
| SCHEMBL7364566 | 0.69 | CHRNB2 (0.78) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL9242858 | 0.68 | CHRNB4 (0.70) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL9243572 | 0.68 | CHRNB4 (0.70) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| Hydrochloric Acid SCHEMBL7516445 | 0.68 | CHRNB2 (0.76) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL6192460 | 0.67 | CHRNB2 (0.63) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL6192462 | 0.67 | CHRNB2 (0.63) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| SCHEMBL29927981 | 0.67 | BACE1 (0.59) | AXL | |
| Hydrochloric Acid SCHEMBL9243326 | 0.67 | CHRNB4 (0.68) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 | |
| Hydrochloric Acid SCHEMBL9243322 | 0.67 | CHRNB4 (0.68) | CHRNB2CHRNB1CHRNB4CHRNA3CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |