Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929230 | 0.81 | IKBKB (0.61) | KDM4EMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL14478873 | 0.73 | ALDH1A1 (0.60) | KDM4EALDH1A1GAAMAPK1MAPT | |
| SCHEMBL29928021 | 0.72 | KDR (0.50) | ALDH1A1GAAMAPTLMNAMEN1 | |
| SCHEMBL2977154 | 0.71 | ALDH1A1 (0.61) | KDM4EALDH1A1GAAMAPK1MAPT | |
| SCHEMBL14825132 | 0.71 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPK1MAPT | |
| SCHEMBL29285926 | 0.70 | KDM4E (0.62) | KDM4EALDH1A1GAAMAPK1MAPT | |
| SCHEMBL4416533 | 0.68 | ALDH1A1 (0.61) | KDM4EALDH1A1GAAMAPK1MAPT | |
| SCHEMBL13708950 | 0.68 | ALDH1A1 (0.66) | KDM4EALDH1A1GAAMAPK1MAPT | |
| SCHEMBL7062128 | 0.68 | KDM4E (0.83) | KDM4EALDH1A1GAAMAPK1MAPT | |
| SCHEMBL12778882 | 0.66 | IKBKB (0.54) | KDM4EMAPTLMNASMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |