Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
| ▸ | GPR39 | O43194 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436672 | 1.00 | KDM4E (0.57) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29929405 | 0.86 | KDM4E (0.57) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19436797 | 0.86 | KDM4E (0.57) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19436715 | 0.83 | KDM4E (0.43) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19436711 | 0.83 | KDM4E (0.43) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19436645 | 0.81 | KDM4E (0.58) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29929502 | 0.81 | KDM4E (0.58) | KDM4EMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19455731 | 0.80 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1HPGDUSP2 | |
| SCHEMBL19436695 | 0.80 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1HPGDUSP2 | |
| SCHEMBL19455423 | 0.80 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311887-B | Pyrazolo [1,5-a ] pyrimidinecarboxamide compounds and their use in the treatment of medical conditions | BIAL研发投资股份有限公司 | 2022-09-13 | — | — | CN | disclosed |