Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19436798 | 1.00 | HSD17B10 (0.54) | HSD17B10ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL19436650 | 0.99 | HSD17B10 (0.53) | HSD17B10ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL19436646 | 0.99 | HSD17B10 (0.53) | HSD17B10ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL19436647 | 0.91 | HSD17B10 (0.45) | HSD17B10ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL29929061 | 0.89 | KDM4E (0.60) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19436708 | 0.89 | KDM4E (0.60) | HSD17B10ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL19436746 | 0.88 | ALDH1A1 (0.57) | HSD17B10ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL19436667 | 0.87 | HSD17B10 (0.68) | HSD17B10ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL19436621 | 0.87 | ALDH1A1 (0.56) | HSD17B10ALDH1A1KDM4ELMNAMEN1 | |
| SCHEMBL19436735 | 0.86 | HSD17B10 (0.67) | HSD17B10ALDH1A1KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311887-B | Pyrazolo [1,5-a ] pyrimidinecarboxamide compounds and their use in the treatment of medical conditions | BIAL研发投资股份有限公司 | 2022-09-13 | — | — | CN | disclosed |