Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | IKBKB | O14920 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KPNA2 | P52292 | 1/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.50 |
| ▸ | CDK2 | P24941 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986074 | 1.00 | CYP1A2 (0.66) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL12330249 | 0.84 | CYP1A2 (0.62) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL2434868 | 0.81 | CDK2 (0.74) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL13373267 | 0.80 | CYP1A2 (0.58) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL5472904 | 0.80 | CYP1A2 (1.00) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL4990063 | 0.78 | KDM4E (1.00) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL29929816 | 0.78 | KDM4E (1.00) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL11296578 | 0.78 | LMNA (1.00) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL11296744 | 0.76 | IKBKB (0.73) | CYP1A2CYP3A4GAACYP2C19KDM4E | |
| SCHEMBL5469070 | 0.76 | KDM4E (1.00) | CYP1A2CYP3A4GAACYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551105-B | Substituted triazoles useful as AXL inhibitors | 里格尔制药公司 | 2022-10-18 | — | — | CN | disclosed |