Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.95 |
| ▸ | DRD2 | P14416 | 5/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.55 |
| ▸ | ANPEP | P15144 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428767 | 0.98 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL42952 | 0.98 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL896147 | 0.98 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL30038968 | 0.98 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL30368725 | 0.98 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL895905 | 0.98 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Hydrochloric Acid SCHEMBL4109114 | 0.95 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Ammonia Solution, Strong SCHEMBL20530707 | 0.95 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Hydrochloric Acid SCHEMBL5518794 | 0.95 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Hydrochloric Acid SCHEMBL756199 | 0.95 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427183-A2 | THERAPEUTIC COMPOUNDS | University of Florida Research Foundation, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129048-A2 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-11-11 | — | — | WO | disclosed |