Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 1.00 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | DRD3 | P35462 | 5/20 | 0.57 |
| ▸ | ANPEP | P15144 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895905 | 1.00 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL896147 | 1.00 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL30368725 | 1.00 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL29428767 | 1.00 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| SCHEMBL30038968 | 1.00 | PLAU (1.00) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Hydrochloric Acid SCHEMBL756199 | 0.98 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Charcoal, Activated SCHEMBL6230334 | 0.98 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Ammonia Solution, Strong SCHEMBL20530707 | 0.98 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Hydrochloric Acid SCHEMBL8991950 | 0.98 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 | |
| Benzene SCHEMBL299297 | 0.98 | PLAU (0.95) | PLAUDRD2DRD3ANPEPOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2014 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370497-A1 | SEROTONIN 5-HT2A, 5-HT2B, AND 5-HT2C RECEPTOR INVERSE AGONISTS | Northeastern University (US) | 2024-05-22 | — | — | EP | claimed |
| WO-2023214011-A1 | ENZYMATIC METHOD FOR PREPARING (R)-3-AMINO-4-ARYL-BUTANOIC ACID DERIVATIVES | ENZYMICALS AG (DE) | 2023-11-09 | — | — | WO | claimed |
| EP-4273254-A1 | ENZYMATIC METHOD FOR PREPARING (R)-3-AMINO-4-ARYL-BUTANOIC ACID DERIVATIVES | Enzymicals AG (DE) | 2023-11-08 | — | — | EP | claimed |
| WO-2023288027-A1 | SEROTONIN 5-HT2A, 5-HT2B, AND 5-HT2C RECEPTOR INVERSE AGONISTS | NORTHEASTERN UNIVERSITY (US) | 2023-01-19 | — | — | WO | claimed |
| CN-114539234-A | Synthesis method and application of C5-2-fatty amino pyrimidine azole compound | 深圳湾实验室 | 2022-05-27 | — | — | CN | claimed |
| CN-109456265-B | Process for producing 2-aminotetralin derivative and intermediate thereof | 上海健康医学院 | 2021-08-13 | — | — | CN | claimed |
| US-20200060997-A1 | TARR Receptor Agonists for Sexual Dysfunction | JOHN MCCOY | 2020-02-27 | — | — | US | claimed |
| CN-109456265-A | The Preparation Method And Their Intermediate of 2- amino tetralin derivative | 上海健康医学院 | 2019-03-12 | — | — | CN | claimed |
| CN-104263800-B | The preparation method of S-2- tetrahydronaphthalene amines | 六安佳诺生化科技有限公司 | 2018-09-14 | — | — | CN | claimed |
| CN-104263801-B | A kind of preparation method of R-2- tetrahydronaphthalene amines | 六安佳诺生化科技有限公司 | 2018-09-11 | — | — | CN | claimed |
| EP-0270947-B1 | SUBSTITUTED BASIC 2-AMINOTETRALINES | BAYER AG (DE) | 1993-05-19 | — | — | EP | claimed |
| EP-0420064-A2 | Substituted 2-amidotetralins as melatonin agonists and antagonists | NORTHWESTERN UNIVERSITY (US) | 1991-04-03 | — | — | EP | claimed |
| EP-0385658-A1 | Ring-substituted 2-amino 1,2,3,4-tetra-hydronaphthalenes and 3-aminochromanes | ELI LILLY AND COMPANY (US) | 1990-09-05 | — | — | EP | claimed |
| CN-1045099-A | Ring-substituted 2-amino-1, 2, 3, 4-tetrahydronaphthalenes and 3-aminochromanes | LILLY CO ELI (US) | 1990-09-05 | — | — | CN | claimed |
| CN-87101285-A | 8-replaces-2-amino-1,2,3, the 4-tetrahydro-bitter edible plant | — | 1988-08-17 | — | — | CN | claimed |
| EP-0272534-A2 | 8-substituted 2-aminotetralins | BAYER AG (DE) | 1988-06-29 | — | — | EP | claimed |
| EP-0270947-A2 | Substituted basic 2-aminotetralines | BAYER AG (DE) | 1988-06-15 | — | — | EP | claimed |
| EP-0148440-A1 | 1,3,4,5-Tetrahydrobenzo(c,d)indoles, process for their preparation and their uses | Troponwerke GmbH & Co. KG (DE) | 1985-07-17 | — | — | EP | claimed |
| US-3984464-A | ANTIARRHYTHMIA AGENTS | A. CHRISTIAENS SOCIETE ANONYME (BE) | 1976-10-05 | — | — | US | claimed |
| US-3943172-A | ANTIARRHYTHMIA | A. CHRISTIAENS, SOCIETE ANONYME (BE) | 1976-03-09 | — | — | US | claimed |