Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 5/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 5/20 | 1.00 |
| ▸ | CHRM3 | P20309 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930634 | 0.99 | CHRM2 (0.97) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL28643449 | 0.86 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL29930410 | 0.86 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL29930463 | 0.85 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL28660495 | 0.85 | CHRM2 (0.72) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL28652129 | 0.84 | CHRM2 (0.71) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL11673002 | 0.77 | CHRM2 (0.63) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL8366931 | 0.75 | CHRM2 (0.59) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| Hydrochloric Acid SCHEMBL5367455 | 0.74 | CHRM2 (0.57) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL4075043 | 0.72 | CHRM2 (0.56) | CHRM2CHRM4CHRM1CHRM3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527172-B | M2 acetylcholine receptor antagonists and uses thereof | 上海交通大学医学院附属仁济医院 | 2022-10-25 | — | — | CN | disclosed |