Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.71 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.71 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660495 | 0.99 | CHRM2 (0.72) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL29930634 | 0.85 | CHRM2 (0.97) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL29930211 | 0.84 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL29930246 | 0.84 | GRIN2B (0.57) | KMT2AMEN1LMNAGRIN2BTHRB | |
| SCHEMBL29930196 | 0.83 | GRIN2B (0.58) | KMT2AMEN1LMNAGRIN2BCYP1A2 | |
| SCHEMBL29930463 | 0.74 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL28643449 | 0.73 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL29930410 | 0.73 | CHRM2 (1.00) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL3067363 | 0.65 | L3MBTL1 (0.64) | KMT2AMEN1THRBCYP1A2CYP3A4 | |
| SCHEMBL11673002 | 0.65 | CHRM2 (0.63) | CHRM2CHRM4CHRM1CHRM3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527172-B | M2 acetylcholine receptor antagonists and uses thereof | 上海交通大学医学院附属仁济医院 | 2022-10-25 | — | — | CN | disclosed |
| CN-113527172-A | M2 acetylcholine receptor antagonists and uses thereof | 上海交通大学医学院附属仁济医院 | 2021-10-22 | — | — | CN | disclosed |