Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28894034 | 1.00 | MAPK14 (0.44) | MAPK14THRBMAPTNPC1RAB9A | |
| SCHEMBL154089 | 0.83 | MAPK14 (0.47) | MAPK14MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL28894135 | 0.82 | MAPT (0.39) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL29930304 | 0.82 | TDO2 (0.40) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL153851 | 0.82 | KDM4E (0.44) | MAPK14MAPTNPC1RAB9AMAPK1 | |
| SCHEMBL29930134 | 0.82 | MAPT (0.39) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL157234 | 0.82 | MAPT (0.45) | THRBMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL28894228 | 0.82 | TDO2 (0.40) | MAPTNPC1RAB9AMAPK1KMT2A | |
| SCHEMBL29929589 | 0.82 | MAPT (0.45) | THRBMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL143394 | 0.78 | TNFRSF1A (0.46) | MAPTNPC1RAB9AMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043847-B | Preparation method of 10H-indolo [1,2-a ] indol-10-one compound | 西北师范大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-115043847-A | Preparation method of 10H-indolo [1,2-a ] indol-10-one compound | 西北师范大学 | 2022-09-13 | — | — | CN | disclosed |