Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 11/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27031088 | 1.00 | DDB1 (0.38) | DDB1CRBNGPR119USP30NAMPT | |
| SCHEMBL29930874 | 0.94 | DDB1 (0.40) | DDB1CRBNGPR119USP30 | |
| SCHEMBL27031146 | 0.94 | DDB1 (0.40) | DDB1CRBNGPR119USP30 | |
| SCHEMBL29930570 | 0.93 | BACE1 (0.41) | DDB1CRBN | |
| SCHEMBL27031189 | 0.93 | BACE1 (0.41) | DDB1CRBN | |
| SCHEMBL29930514 | 0.92 | DDB1 (0.41) | DDB1CRBNGPR119 | |
| SCHEMBL27031107 | 0.92 | DDB1 (0.41) | DDB1CRBNGPR119 | |
| SCHEMBL29930726 | 0.90 | DDB1 (0.39) | DDB1CRBNGPR119 | |
| SCHEMBL27031216 | 0.90 | DDB1 (0.39) | DDB1CRBNGPR119 | |
| SCHEMBL29930608 | 0.87 | CHRM2 (0.34) | DDB1CRBNGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308559-A1 | BENZISOXAZOLE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022195355-A1 | BENZISOXAZOLE DERIVATIVES AND USES THEREOF | NOVARTIS AG (CH) | 2022-09-22 | — | — | WO | disclosed |