Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 13/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.53 |
| ▸ | USP2 | O75604 | 10/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23411493 | 1.00 | CYP3A4 (0.53) | CYP3A4HSD17B10USP2TSHRMEN1 | |
| SCHEMBL18831899 | 0.93 | USP2 (0.58) | CYP3A4HSD17B10USP2TSHRMEN1 | |
| SCHEMBL23439554 | 0.87 | CYP3A4 (0.48) | CYP3A4HSD17B10USP2TSHRMEN1 | |
| SCHEMBL23411518 | 0.87 | CYP3A4 (0.55) | CYP3A4HSD17B10USP2TSHRMEN1 | |
| SCHEMBL23412152 | 0.86 | CYP3A4 (0.64) | CYP3A4HSD17B10USP2TSHRMEN1 | |
| SCHEMBL23439556 | 0.84 | CYP3A4 (0.58) | CYP3A4HSD17B10USP2TSHRMEN1 | |
| SCHEMBL29933338 | 0.84 | FFAR4 (0.50) | CYP3A4HSD17B10USP2TSHRMEN1 | |
| SCHEMBL23411183 | 0.84 | FFAR4 (0.50) | CYP3A4HSD17B10USP2TSHRMEN1 | |
| SCHEMBL2385957 | 0.84 | ABCB1 (0.59) | CYP3A4MEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL29556504 | 0.84 | ABCB1 (0.59) | CYP3A4MEN1KMT2AALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115210238-B | Substituted aminoquinolones as dgkα inhibitors for immune activation | 拜耳公司 | 2024-08-27 | — | — | CN | disclosed |
| CN-115210238-A | Substituted aminoquinolones as DGK alpha inhibitors for immune activation | 拜耳公司 | 2022-10-18 | — | — | CN | disclosed |