Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.73 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.73 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933795 | 1.00 | HDAC1 (0.73) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL29934167 | 0.99 | HDAC1 (0.70) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL1520144 | 0.88 | HDAC1 (0.64) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL29768662 | 0.84 | MTNR1A (0.54) | HDAC1HDAC2HDAC8HDAC3MTNR1A | |
| SCHEMBL19182734 | 0.84 | MTNR1A (0.54) | HDAC1HDAC2HDAC8HDAC3MTNR1A | |
| SCHEMBL1121805 | 0.84 | MTNR1A (0.54) | HDAC1HDAC2HDAC8HDAC3MTNR1A | |
| SCHEMBL28879508 | 0.84 | MTNR1A (0.54) | HDAC1HDAC2HDAC8HDAC3MTNR1A | |
| SCHEMBL6256471 | 0.82 | MTNR1A (0.55) | HDAC1HDAC2HDAC8HDAC3MTNR1A | |
| SCHEMBL3380994 | 0.81 | HDAC1 (0.73) | HDAC1HDAC2HDAC8HDAC3HDAC6 | |
| SCHEMBL3381105 | 0.81 | HDAC1 (0.73) | HDAC1HDAC2HDAC8HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879790-B | Amide micromolecule organic compound with indole or indole analogue as mother nucleus structure, application and preparation method thereof | 华东师范大学 | 2022-09-20 | — | — | CN | claimed |
| CN-109879790-B | Amide micromolecule organic compound with indole or indole analogue as mother nucleus structure, application and preparation method thereof | 华东师范大学 | 2022-09-20 | — | — | CN | disclosed |