Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA4 | P22748 | 3/20 | 0.32 |
| ▸ | CA6 | P23280 | 3/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29933807 | 0.78 | CA1 (0.38) | TUBB1PTGS2MEN1KMT2AMAPT | |
| SCHEMBL28644753 | 0.78 | CA1 (0.38) | TUBB1PTGS2MEN1KMT2AMAPT | |
| SCHEMBL14964084 | 0.70 | MEN1 (0.36) | TUBB1MEN1KMT2AMAPTALOX15 | |
| SCHEMBL4922559 | 0.68 | CA2 (0.44) | TUBB1MEN1KMT2AMAPTALOX15 | |
| SCHEMBL23462104 | 0.67 | ALOX5AP (0.36) | TUBB1PTGS2MEN1KMT2AMAPT | |
| SCHEMBL30001501 | 0.67 | ALOX5AP (0.36) | TUBB1PTGS2MEN1KMT2AMAPT | |
| SCHEMBL19125049 | 0.67 | SLC5A2 (0.39) | TUBB1PTGS2MEN1KMT2AMAPT | |
| SCHEMBL1539338 | 0.67 | SLC5A2 (0.51) | TUBB1SLC5A2ALDH1A1KDM4EGAA | |
| SCHEMBL24199854 | 0.67 | SLC5A1 (0.43) | TUBB1PTGS2MAPTSLC5A2CA2 | |
| SCHEMBL14725631 | 0.67 | NQO2 (0.40) | TUBB1MEN1KMT2AMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461659-B | C-spirocyclic prostaglandin analogue intermediate and preparation method thereof | 上海应用技术大学 | 2022-11-11 | — | — | CN | claimed |
| CN-113461659-B | C-spirocyclic prostaglandin analogue intermediate and preparation method thereof | 上海应用技术大学 | 2022-11-11 | — | — | CN | disclosed |