Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5027205 | 1.00 | CYP2A6 (0.48) | CYP2A6DYRK1BDYRK1AMEN1PSIP1 | |
| Hydrochloric Acid SCHEMBL23501615 | 0.98 | CYP2A6 (0.47) | CYP2A6DYRK1BDYRK1AMEN1PSIP1 | |
| Hydrochloric Acid SCHEMBL29933924 | 0.98 | CYP2A6 (0.47) | CYP2A6DYRK1BDYRK1AMEN1PSIP1 | |
| SCHEMBL17546483 | 0.77 | ADRB2 (0.41) | CYP2A6DYRK1AMEN1PSIP1AXL | |
| SCHEMBL14955802 | 0.77 | ADRB2 (0.41) | CYP2A6DYRK1AMEN1PSIP1AXL | |
| SCHEMBL15220476 | 0.76 | CYP2A6 (0.56) | CYP2A6DYRK1BDYRK1AMEN1PSIP1 | |
| SCHEMBL12117526 | 0.74 | CYP2A6 (0.48) | CYP2A6DYRK1ACYP11B2CYP11B1 | |
| SCHEMBL23501651 | 0.74 | CYP2A6 (0.48) | CYP2A6DYRK1BDYRK1AMEN1KDM4E | |
| SCHEMBL5799279 | 0.74 | PTK2 (0.52) | CYP2A6MEN1KDM4EALDH1A1KMT2A | |
| SCHEMBL23501621 | 0.74 | CYP2A6 (0.48) | CYP2A6MKNK1MKNK2CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |