Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501618 | 1.00 | CYP2A6 (0.52) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL23501643 | 1.00 | CYP2A6 (0.52) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL5218298 | 0.86 | MKNK1 (0.56) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL5848606 | 0.86 | MKNK1 (0.56) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL23501646 | 0.86 | CTSL (0.46) | MKNK1MKNK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL23501645 | 0.86 | CTSL (0.46) | MKNK1MKNK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL13086472 | 0.86 | CYP2A6 (0.56) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL29934054 | 0.86 | CTSL (0.46) | MKNK1MKNK2CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29337469 | 0.82 | CYP2A6 (0.56) | CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1 | |
| SCHEMBL1455475 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |