Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CD38 | P28907 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19947447 | 1.00 | MAPK1 (0.42) | MAPK1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22574279 | 0.88 | SMYD3 (0.43) | SMYD3ALDH1A1KDM4ENPC1LMNA | |
| SCHEMBL3515522 | 0.84 | ALDH1A1 (0.41) | MAPK1SMYD3KCNH2ALDH1A1KDM4E | |
| SCHEMBL29934021 | 0.83 | KCNH2 (0.36) | SMYD3KCNH2ALDH1A1KDM4ENPC1 | |
| SCHEMBL23501595 | 0.83 | KCNH2 (0.36) | SMYD3KCNH2ALDH1A1KDM4ENPC1 | |
| SCHEMBL15829423 | 0.80 | MAPK1 (0.54) | MAPK1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL19984630 | 0.80 | PIM1 (0.43) | MAPK1RIPK2SMYD3ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL19947446 | 0.79 | PIM1 (0.42) | MAPK1RIPK2SMYD3ALDH1A1HSD17B10 | |
| SCHEMBL19947310 | 0.78 | RIPK2 (0.44) | RIPK2 | |
| SCHEMBL23501662 | 0.78 | POLB (0.47) | RIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |