Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.46 |
| ▸ | CTSA | P10619 | 4/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108185 | 0.83 | KDM1A (0.53) | MKNK1MKNK2CYP11B2CYP11B1CHRNB4 | |
| SCHEMBL27932352 | 0.81 | MKNK1 (0.50) | MKNK1MKNK2CYP11B2CYP11B1CHRNB4 | |
| SCHEMBL3636122 | 0.79 | NR1H4 (0.56) | NR1H4BRD4 | |
| SCHEMBL5434680 | 0.79 | HPGD (0.47) | CTSA | |
| SCHEMBL2488476 | 0.78 | MKNK1 (0.77) | MKNK1MKNK2CYP11B2CYP11B1SIRT2 | |
| SCHEMBL31395151 | 0.78 | CYP2A6 (0.54) | MKNK1MKNK2CYP11B2CYP11B1DRD1 | |
| SCHEMBL6754398 | 0.77 | MKNK1 (0.67) | MKNK1MKNK2CYP11B2CYP11B1SIRT2 | |
| SCHEMBL30108228 | 0.77 | CYP2A6 (0.70) | MKNK1MKNK2CYP11B2CYP11B1DRD1 | |
| SCHEMBL18618142 | 0.77 | MKNK1 (0.47) | MKNK1MKNK2CYP11B2CYP11B1DRD1 | |
| SCHEMBL29588040 | 0.77 | MKNK1 (0.47) | MKNK1MKNK2CYP11B2CYP11B1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |