Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 9/20 | 0.67 |
| ▸ | MKNK2 | Q9HBH9 | 9/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2488476 | 0.88 | MKNK1 (0.77) | MKNK1MKNK2CYP11B2CYP11B1MAP4K4 | |
| SCHEMBL30108186 | 0.88 | MKNK1 (0.65) | MKNK1MKNK2CYP11B2CYP11B1MAP4K4 | |
| SCHEMBL2841794 | 0.87 | SIRT2 (0.54) | MKNK1MKNK2CYP11B2CYP11B1MAP4K4 | |
| SCHEMBL1785559 | 0.87 | MKNK1 (0.68) | MKNK1MKNK2CYP11B2CYP11B1MAP4K4 | |
| SCHEMBL28760070 | 0.87 | MKNK1 (0.57) | MKNK1MKNK2CYP11B2CYP11B1MAP4K4 | |
| SCHEMBL31242967 | 0.87 | CYP11B2 (0.55) | MKNK1MKNK2CYP11B2CYP11B1MAP4K4 | |
| SCHEMBL27987797 | 0.87 | CYP11B2 (0.55) | MKNK1MKNK2CYP11B2CYP11B1MAP4K4 | |
| SCHEMBL13188346 | 0.85 | MKNK1 (0.77) | MKNK1MKNK2CYP11B2CYP11B1CHEK2 | |
| SCHEMBL30108236 | 0.85 | MKNK1 (0.77) | MKNK1MKNK2CYP11B2CYP11B1CHEK2 | |
| SCHEMBL12647206 | 0.85 | MKNK1 (0.69) | MKNK1MKNK2CYP11B2CYP11B1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1264820-A1 | NOVEL AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087798-A1 | Novel amide compounds | H1-2, H1-0, H1-3 | MKNK1 2259/4885MKNK2 1676/4885CYP11B2 825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.