SCHEMBL29933971

SCHEMBL29933971

Oc1cncc(-c2ncccn2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.48
HSD17B1 P14061 3/20 0.44
CYP11B1 P15538 6/20 0.39
CYP11B2 P19099 6/20 0.39
CYP17A1 P05093 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP19A1 P11511 2/20 0.37
HSD17B2 P37059 2/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
APLNR P35414 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
KDM4E B2RXH2 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23501651 1.00 CYP2A6 (0.48) CYP2A6HSD17B1CYP11B1CYP11B2CYP17A1
SCHEMBL6068143 0.77 BACE1 (0.42) CYP2A6HSD17B1CYP3A4CYP19A1HSD17B2
SCHEMBL8334091 0.76 CYP2A6 (0.56) CYP2A6HSD17B1CYP11B1CYP11B2HSD17B2
Hydrochloric Acid SCHEMBL6067839 0.75 BACE1 (0.40) CYP2A6HSD17B1CYP3A4CYP19A1HSD17B2
SCHEMBL12117526 0.74 CYP2A6 (0.48) CYP2A6CYP11B1CYP11B2CYP3A4DYRK1A
SCHEMBL5799279 0.74 PTK2 (0.52) CYP2A6CYP11B1CYP11B2CYP19A1NPC1
SCHEMBL5027205 0.74 CYP2A6 (0.48) CYP2A6CYP11B1CYP11B2PIK3CGNPC1
SCHEMBL23501621 0.74 CYP2A6 (0.48) CYP2A6CYP11B1CYP11B2CYP3A4CYP19A1
SCHEMBL29933932 0.74 CYP2A6 (0.48) CYP2A6CYP11B1CYP11B2PIK3CGNPC1
SCHEMBL1319171 0.74 MKNK1 (0.53) CYP2A6KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025021182-A1 CYP11A1 INHIBITORS ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) 2025-01-30 WO disclosed
CN-119371371-A Compounds and compositions as PDGF receptor kinase inhibitors 日本新药株式会社 2025-01-28 CN disclosed
CN-115315421-B Compounds and compositions as PDGF receptor kinase inhibitors 日本新药株式会社 2024-12-03 CN disclosed
CN-115315421-A Compounds and compositions as PDGF receptor kinase inhibitors 日本新药株式会社 2022-11-08 CN disclosed