Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 6/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932961 | 0.85 | CNR1 (0.42) | CNR1CHRM1TACR2GABRA5 | |
| SCHEMBL29932952 | 0.85 | CNR1 (0.42) | CNR1CHRM1TACR2GABRA5 | |
| SCHEMBL29933163 | 0.85 | CHRM1 (0.46) | CNR1CHRM1TACR2GABRA5 | |
| SCHEMBL29934060 | 0.83 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2KDM4EMEN1 | |
| SCHEMBL29935184 | 0.83 | KIT (0.50) | TAS1R3TAS1R1TAS1R2KDM4EMEN1 | |
| SCHEMBL29933247 | 0.83 | CNR1 (0.42) | CNR1CHRM1GABRA5 | |
| SCHEMBL29933394 | 0.81 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2KDM4EMEN1 | |
| SCHEMBL23501594 | 0.80 | POLB (0.44) | KDM4E | |
| SCHEMBL29934040 | 0.80 | POLB (0.44) | KDM4E | |
| SCHEMBL29934160 | 0.78 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |