Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.33 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16419692 | 1.00 | CYP2A6 (0.36) | CYP2A6CYP11B2HCRTR1HCRTR2CYP11B1 | |
| SCHEMBL17800147 | 0.85 | NOTUM (0.36) | HCRTR1HCRTR2RIPK2SCN10A | |
| SCHEMBL16419708 | 0.81 | — | — | |
| SCHEMBL17819625 | 0.75 | KDM4E (0.44) | RIPK2KDM4E | |
| SCHEMBL29464651 | 0.74 | CHRNB2 (0.42) | KDM4E | |
| SCHEMBL2728918 | 0.73 | CYP2A6 (0.47) | CYP2A6CYP11B2CYP11B1ACHEKDM4E | |
| SCHEMBL2130992 | 0.73 | CFTR (0.49) | CYP11B2HCRTR1HCRTR2CYP11B1PRKCI | |
| SCHEMBL17819718 | 0.73 | VHL (0.52) | CYP2A6CYP11B2CYP11B1RIPK2KDM4E | |
| SCHEMBL17781409 | 0.73 | CYP2A6 (0.46) | CYP2A6CYP11B2CYP11B1RIPK2KDM4E | |
| SCHEMBL17819393 | 0.73 | CYP3A4 (0.47) | CYP2A6CYP11B2CYP11B1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |