Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 6/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17818390 | 0.81 | MAPK14 (0.53) | NPC1RAB9AKITDDR1 | |
| SCHEMBL29934118 | 0.81 | TAS1R3 (0.60) | TAS1R3TAS1R1TAS1R2NAMPTNPSR1 | |
| SCHEMBL29934001 | 0.81 | MAPT (0.47) | TAS1R3TAS1R1TAS1R2NAMPTNPSR1 | |
| SCHEMBL29933852 | 0.81 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2NAMPTNPSR1 | |
| SCHEMBL29933960 | 0.81 | CNR1 (0.47) | TAS1R3TAS1R1TAS1R2CNR1 | |
| SCHEMBL29934035 | 0.80 | NPSR1 (0.47) | TAS1R3TAS1R1TAS1R2NAMPTNPSR1 | |
| SCHEMBL29933893 | 0.79 | NAMPT (0.46) | TAS1R3TAS1R1TAS1R2NAMPTNPSR1 | |
| SCHEMBL29933384 | 0.78 | KIT (0.49) | TAS1R3TAS1R1TAS1R2HDAC4HDAC6 | |
| SCHEMBL29933999 | 0.78 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2NAMPTNPSR1 | |
| SCHEMBL29933938 | 0.78 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2NAMPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |