Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 4/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501660 | 1.00 | HCAR2 (0.41) | HCAR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29933977 | 0.86 | HCAR2 (0.44) | HCAR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23501647 | 0.86 | HCAR2 (0.44) | HCAR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL23501627 | 0.85 | ATM (0.46) | LNPEPOPRK1KCNH2ABHD6CLK2 | |
| SCHEMBL31359370 | 0.85 | ATM (0.46) | LNPEPOPRK1KCNH2ABHD6CLK2 | |
| SCHEMBL3931389 | 0.82 | NPC1 (0.47) | HCAR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12168345 | 0.80 | CYP11B1 (0.44) | HCAR2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25312274 | 0.79 | LNPEP (0.40) | KMT2AALDH1A1LMNALNPEPOPRK1 | |
| SCHEMBL30507947 | 0.79 | LNPEP (0.40) | KMT2AALDH1A1LMNALNPEPOPRK1 | |
| SCHEMBL31705286 | 0.75 | CYP11B1 (0.47) | HCAR2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119371371-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2025-01-28 | — | — | CN | disclosed |
| CN-115315421-B | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2024-12-03 | — | — | CN | disclosed |
| CN-115315421-A | Compounds and compositions as PDGF receptor kinase inhibitors | 日本新药株式会社 | 2022-11-08 | — | — | CN | disclosed |