Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 3/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22855324 | 0.94 | LMNA (0.40) | LMNAKMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL22855532 | 0.88 | LMNA (0.38) | LMNAKMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL22855701 | 0.87 | LMNA (0.45) | LMNAKMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL22830069 | 0.86 | LMNA (0.31) | LMNAMAPTCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL22855721 | 0.86 | LMNA (0.41) | LMNAKMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL22855492 | 0.85 | LMNA (0.41) | LMNAKMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL29929081 | 0.84 | LMNA (0.46) | LMNAKMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL22830105 | 0.83 | LMNA (0.31) | LMNAMAPTCYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL16392657 | 0.83 | LMNA (0.40) | LMNAKMT2AMAPTCYP3A4CYP2C19 | |
| SCHEMBL24699867 | 0.83 | TNF (0.41) | LMNAKMT2AMAPTCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4029520-A1 | GALNAC-OLIGONUCLEOTIDE CONJUGATE FOR LIVER-TARGETED DELIVERY USE, AND METHOD FOR PRODUCING SAME | Daiichi Sankyo Company, Limited (JP) | 2022-07-20 | — | — | EP | disclosed |