Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.80 |
| ▸ | PDE5A | O76074 | 1/20 | 0.80 |
| ▸ | PDE9A | O76083 | 1/20 | 0.80 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.80 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.67 |
| ▸ | PYGM | P11217 | 1/20 | 0.67 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.67 |
| ▸ | USP7 | Q93009 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.61 |
| ▸ | GABRP | O00591 | 1/20 | 0.59 |
| ▸ | GABRD | O14764 | 1/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13487369 | 1.00 | PDE4D (0.80) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL13487370 | 1.00 | PDE4D (0.80) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL25038978 | 0.92 | GABRP (0.69) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL25038979 | 0.92 | GABRP (0.69) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL25038975 | 0.92 | GABRP (0.69) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL7163156 | 0.91 | EGFR (0.67) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL29386542 | 0.91 | EGFR (0.67) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL13487367 | 0.90 | POLB (0.68) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL13637888 | 0.90 | POLB (0.68) | PDE4DPDE5APDE9APDE1BPOLB | |
| SCHEMBL24433072 | 0.89 | PDE4D (0.73) | PDE4DPDE5APDE9APDE1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |