Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18197791 | 0.82 | IDO1 (0.42) | IDO1PTPN2PTPN1CDC25BMAOA | |
| SCHEMBL9205144 | 0.81 | PTPN2 (0.38) | IDO1PTPN2PTPN1CDC25B | |
| SCHEMBL24465058 | 0.78 | PTPN2 (0.35) | IDO1PTPN2PTPN1CDC25BDAO | |
| SCHEMBL3635614 | 0.76 | IDO1 (0.40) | IDO1PTPN2PTPN1CDC25BMAOA | |
| SCHEMBL18197823 | 0.76 | PTPN2 (0.38) | IDO1PTPN2PTPN1CDC25B | |
| SCHEMBL8443621 | 0.76 | MAPT (0.40) | PTPN2PTPN1CDC25BMAOASMN1; SMN2 | |
| SCHEMBL2579044 | 0.76 | MAPT (0.40) | PTPN2PTPN1CDC25BMAOASMN1; SMN2 | |
| SCHEMBL8443084 | 0.76 | MAPT (0.40) | PTPN2PTPN1CDC25BMAOASMN1; SMN2 | |
| SCHEMBL8442749 | 0.76 | MAPT (0.40) | PTPN2PTPN1CDC25BMAOASMN1; SMN2 | |
| SCHEMBL1187679 | 0.73 | IDO1 (0.57) | IDO1PTPN2PTPN1CDC25BDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4074704-A1 | QUINOLINE COMPOUNDS WITH ANTI-CANCER ACTIVITY | CanBas Co., Ltd. (JP) | 2022-10-19 | — | — | EP | disclosed |