Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ichthynone SCHEMBL9924621 | 1.00 | BCHE (0.60) | BCHECYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL9924624 | 0.88 | BCHE (0.73) | BCHECYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL30500621 | 0.88 | BCHE (0.63) | BCHECYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL30534406 | 0.87 | BCHE (0.79) | BCHECYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL9924622 | 0.87 | BCHE (0.79) | BCHECYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL29367894 | 0.79 | BCHE (0.76) | BCHECYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL29439362 | 0.75 | BCHE (1.00) | BCHECYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL5094581 | 0.75 | BCHE (1.00) | BCHECYP3A4TP53MAPTSMN1; SMN2 | |
| SCHEMBL4283565 | 0.73 | SMN1; SMN2 (0.51) | CYP3A4MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16694334 | 0.67 | BCHE (1.00) | BCHECYP3A4TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200970-B | Osthole isoxazoline derivatives, and preparation method and application thereof | 郑州大学 | 2023-06-13 | — | — | CN | disclosed |
| US-20230057355-A1 | GENE NETWORKS THAT MEDIATE REMYELINATION OF THE HUMAN BRAIN | UNIVERSITY OF ROCHESTER | 2023-02-23 | — | — | US | disclosed |
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |