Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.32 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.32 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23363880 | 1.00 | CNR2 (0.37) | CNR2MAPTNPSR1NPC1ALDH1A1 | |
| SCHEMBL15053030 | 0.85 | CNR2 (0.37) | CNR2MAPTNPSR1NPC1ALDH1A1 | |
| SCHEMBL5783206 | 0.83 | PDE4A (0.37) | CNR2MAPTNPSR1NPC1ALDH1A1 | |
| SCHEMBL22047869 | 0.83 | CNR2 (0.36) | CNR2MAPTNPSR1NPC1ALDH1A1 | |
| SCHEMBL15052560 | 0.83 | CNR2 (0.36) | CNR2MAPTNPSR1NPC1ALDH1A1 | |
| SCHEMBL23383733 | 0.83 | SMN1; SMN2 (0.37) | CNR2MAPTALDH1A1RAB9AHTT | |
| SCHEMBL5779592 | 0.83 | CNR2 (0.36) | CNR2MAPTNPSR1NPC1ALDH1A1 | |
| SCHEMBL21494328 | 0.81 | GABRA1 (0.35) | CNR2MAPTNPSR1NPC1ALDH1A1 | |
| SCHEMBL19330286 | 0.81 | MAPT (0.35) | MAPTALDH1A1SLC13A5SLC13A2SLC13A3 | |
| SCHEMBL16318902 | 0.80 | CNR2 (0.39) | CNR2MAPTNPSR1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112805267-B | Carboxamide and sulfonamide derivatives as TEAD modulators | 豪夫迈·罗氏有限公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-4058435-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | Genentech, Inc. (US) | 2022-09-21 | — | — | EP | disclosed |