Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MARK4 | Q96L34 | 2/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3082113 | 0.84 | MAPT (0.45) | PGRRORARORCRORBMAPT | |
| SCHEMBL30046327 | 0.82 | GPR3 (0.46) | MAPTLMNAALDH1A1IMPDH2KDM4E | |
| SCHEMBL30633063 | 0.82 | GPR3 (0.46) | MAPTLMNAALDH1A1IMPDH2KDM4E | |
| SCHEMBL2258634 | 0.82 | GPR3 (0.46) | MAPTLMNAALDH1A1IMPDH2KDM4E | |
| SCHEMBL4985558 | 0.82 | MAPT (0.41) | PGRRORARORCRORBMAPT | |
| SCHEMBL27426783 | 0.79 | BCHE (0.46) | PGRRORARORCRORBMAPT | |
| SCHEMBL22166470 | 0.79 | PTGER4 (0.56) | MAPTHTTLMNAHPGDALDH1A1 | |
| SCHEMBL881552 | 0.77 | GPR3 (0.67) | PGRRORARORCRORBMAPT | |
| SCHEMBL23491106 | 0.76 | BCHE (0.44) | PGRRORARORCRORBMAPT | |
| SCHEMBL23352488 | 0.76 | BCHE (0.44) | PGRRORARORCRORBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220291237-A1 | Gene Expression Inflammatory Age and Its Uses | Edifice Health, Inc. (US) | 2022-09-15 | — | — | US | disclosed |