Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24722820 | 0.87 | BRD4 (0.48) | BRD4ALDH3A1HTTALDH1A1MEN1 | |
| SCHEMBL19250520 | 0.85 | CA1 (0.47) | BRD4L3MBTL1POLBALDH3A1HTT | |
| SCHEMBL30461664 | 0.82 | ALDH1A1 (0.43) | BRD4L3MBTL1POLBALDH3A1HTT | |
| SCHEMBL25419377 | 0.82 | ALDH1A1 (0.43) | BRD4L3MBTL1POLBALDH3A1HTT | |
| SCHEMBL30399721 | 0.81 | HPGD (0.42) | BRD4L3MBTL1POLBALDH3A1HTT | |
| SCHEMBL26176367 | 0.81 | HPGD (0.42) | BRD4L3MBTL1POLBALDH3A1HTT | |
| SCHEMBL18995268 | 0.81 | BRD4 (0.51) | BRD4L3MBTL1POLBALDH3A1HTT | |
| SCHEMBL31150811 | 0.81 | BRD4 (0.51) | BRD4L3MBTL1POLBALDH3A1HTT | |
| SCHEMBL19250316 | 0.79 | BRD4 (0.54) | BRD4L3MBTL1POLBALDH3A1HTT | |
| SCHEMBL12066672 | 0.76 | BRD4 (0.51) | BRD4L3MBTL1POLBALDH3A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073472-A | Condensed bicyclic compound, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-09-20 | — | — | CN | disclosed |