Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MDM4 | O15151 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1168385 | 1.00 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL1168384 | 1.00 | SMN1; SMN2 (0.65) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL979806 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL979804 | 0.87 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL1226435 | 0.87 | ABCG2 (0.58) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL909922 | 0.87 | POLB (0.59) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL1226433 | 0.87 | ABCG2 (0.58) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL909921 | 0.87 | POLB (0.59) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL8153652 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2HPGDLMNAALOX12ATM | |
| SCHEMBL1405023 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2HPGDLMNAALOX12ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4073242-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY | Kumquat Biosciences Inc. (US) | 2022-10-19 | — | — | EP | disclosed |