Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909921 | 1.00 | POLB (0.59) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL18046773 | 0.87 | POLB (0.47) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL29935336 | 0.87 | SMN1; SMN2 (0.65) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL1168385 | 0.87 | SMN1; SMN2 (0.65) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL1168384 | 0.87 | SMN1; SMN2 (0.65) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL18046772 | 0.87 | POLB (0.47) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL11853194 | 0.86 | POLB (0.50) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL11853199 | 0.86 | POLB (0.50) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL976869 | 0.84 | POLB (0.56) | POLBKMT2AMEN1MAPTRAB9A | |
| SCHEMBL976868 | 0.84 | POLB (0.56) | POLBKMT2AMEN1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112338091-B | Punch forming process of aluminum alloy radiating fin | 太仓巧洲五金科技有限公司 | 2022-08-02 | — | — | CN | claimed |
| CN-106701274-B | Punching oil composition | 浙江海洋大学 | 2019-12-17 | — | — | CN | claimed |
| EP-1429768-B1 | NOVEL MEDICAMENTS FOR INHALATION | BOEHRINGER INGELHEIM PHARMA (DE) | 2016-11-16 | — | — | EP | claimed |
| US-20050256149-A1 | Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-11-17 | — | — | US | claimed |
| US-6919325-B2 | Respiratory system disorders; synergistic mixtures | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-07-19 | — | — | US | claimed |
| US-20030130300-A1 | Respiratory system disorders; synergistic mixtures | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-07-10 | — | — | US | claimed |
| CN-117343072-A | 1-substituted cinnamoyl-2-oxo lycorine compound and preparation method and application thereof | 山东达因海洋生物制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-114014905-B | Glycyrrhetinic acid derivative targeting PPARgamma as well as preparation method and application thereof | 浙江科技学院 | 2023-07-21 | — | — | CN | disclosed |
| WO-2023000398-A1 | LYCORINE β-ARYL ACRYLATE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 山东达因海洋生物制药股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| CN-112338091-B | Punch forming process of aluminum alloy radiating fin | 太仓巧洲五金科技有限公司 | 2022-08-02 | — | — | CN | disclosed |
| CN-113416199-B | Lycorine beta-aryl acrylate derivative and preparation method and application thereof | 山东达因海洋生物制药股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-114014905-A | PPAR gamma targeted glycyrrhetinic acid derivative and preparation method and application thereof | 浙江科技学院 | 2022-02-08 | — | — | CN | disclosed |
| CN-113416199-A | Lycorine beta-aryl acrylate derivative and preparation method and application thereof | 山东达因海洋生物制药股份有限公司 | 2021-09-21 | — | — | CN | disclosed |
| US-4654346-A | Fungicidal N,N-disubstituted-heterocyclic carboxamides | CHEVRON RESEARCH COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| US-4544670-A | ANTIPROTOZOA AGENTS, GASTROINTESTINAL AND CARDIOVASCULAR DISORDERS | WILLIAM H. RORER, INC. (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0116639-A4 | ACYL GUANIDINES. | RORER INTERNAT OVERSEAS INC (US) | 1985-09-25 | — | — | EP | disclosed |
| US-4504484-A | Certain N,N-di-substituted-pyridine carboxamides, fungicidal compositions and fungicidal method of use | CHEVRON RESEARCH COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| EP-0116639-A1 | ACYL GUANIDINES | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| WO-1984000875-A1 | ACYL GUANIDINES | RORER INT OVERSEAS (US) | 1984-03-15 | — | — | WO | disclosed |
| US-4247597-A | Electroscopic carrier particles having a carboxylic acid surface treatment | PITNEY BOWES, INC. (US) | 1981-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256149-A1 | Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts | ADRB3, ADRB1, HSD3B1 | POLB 604/4885KMT2A 3395/4885MEN1 3928/4885 |
| US-20030130300-A1 | Respiratory system disorders; synergistic mixtures | ADRB3, ADRB1, CHRM3 | POLB 449/4885KMT2A 4356/4885MEN1 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.